Brain development sexuality and reproduction - Reframing sexual differentiation of the brain

Brain development diverges in males and females in response to androgen production by the fetal testis. This sexual differentiation of the brain...

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  • Exposure to estrogen can cause certain parts of the brain to develop differently.
  • Brain development diverges in males and females in response to androgen . sex differences in the brain were relegated to...
  • Teen Sex May Affect Brain Development, Study Suggests
  • In the twentieth century, the dominant model of sexual differentiation stated that genetic sex XX versus XY...

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The Human Reproduction

Hormones plus experience "We used the opportunity to have sex, which naturally increases testosterone levels, to see whether these experiences during early life would have long-term consequence," co-author Zachary Weil, a research assistant professor of neuroscience at Ohio State, told LiveScience. The offset of the critical period is determined by finding the developmental stage at which females lose sensitivity to exogenous steroid treatment; in other words, they cannot be masculinized.

The best studied is the four core genotypes FCG model, in which the complement of sex chromosomes XX versus XY is made independent of gonadal sex 12 , 27 , However, a number of variables that differ in males and females are robustly influenced by sex chromosome complement, with genetic sex exerting influences sometimes as large as those exerted by gonadal hormones.

Prostaglandin E2 stimulates estradiol synthesis in the cerebellum postnatally with associated effects on purkinje neuron dendritic arbor and electrophysiological properties. He achieved this by removing Sry from the Y chromosome and replacing it on an autosome, which allowed for XX females to develop testes and XY males to develop ovaries. Equally rare are those with XYY, which allows for investigation of the opposite question—does the number of Y chromosomes matter?

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Classic model: hormone-mediated organization/activation
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The uproar that followed a November episode of Fox's "Glee" in which two teen couples had sex for the first time may have some scientific legs.

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